Ikoria: Lair of Behemoths is the 84th Magic expansion. The set is noted to be about "building your own monsters" and will feature a new mechanic to represent this. This is possibly the Mutate mechanic. The set is mostly designed bottom-up, but there are also some top-down individual card designs. The setting is Ikoria, a plane of beasts and monsters. Each booster box contains a box topper.

The set comes with five Commander decks (Ikoria Commander). This is essentially Commander 2020 aligning with Ikoria: Lair of Behemoths. The 71 new cards in the decks are set on the world of Ikoria, but the reprints can be from anywhere. There are a handful of cards from the main Ikoria set in these decks in the reprint slots, but the number is fairly small.